Delivery of Intact Transcription Factor by Using Self-Assembled Supraniolecular Nanoparticles

摘要

Protein delivery has been considered as the most straightforward strategy for modulating cellular behavior without the safety concerns and expression performance issues associated with gene deliver approaches. Two major challenges remain to be overcome in order to enable practical applications in biology and medicine 1) how to foster cellular uptake of protein molecules and 2) how to retain their stabilities and functions over the delivery process.