Towards Direct Mukaiyama-Type Reactions Catalytic in Silicon

摘要

Silicon is one of the most abundant elements on Earth, and silicon-containing reagents are useful tools in organic chemistry, not only as widely applicable protecting groups, but also as reaction components capable of controlling and directing the reaction outcome. Thus, one of the most venerable C—C bond-forming reactions, the aldol addition reaction, has a silicon-mediated version named the Mukaiyama aldol reac-tion after its discoverer.