Modified Nucleosides in Biochemistry, Biotechnology and Medicine

摘要

Nucleoside research, often referred to as a "speciality field", remains ven-erated and ageless. In large part this is due to the profound and wide-ranging roles that nucleosides, their derivatives, and analogues play in biochemistry, biology, and medicine, and as molecular probes. Nucleosides present a scaffold for rich and diverse modifications, and by virtue of their importance, the products of such modifications offer interesting application opportunities that gain greater significance in the post-genomic era.