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首页> 外文期刊>IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control >A reflected-scanned ultrasound system for external simultaneous thermoradiotherapy
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A reflected-scanned ultrasound system for external simultaneous thermoradiotherapy

机译:用于外部同时热放射疗法的反射扫描超声系统

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The simultaneous delivery of hyperthermia and ionizing radiation has the potential to improve clinical outcome. To this purpose, a scanning ultrasound reflector-linear array system (SURLAS) with the ability both to conform power to superficial volumes and to operate concomitantly with medical linear accelerators is currently under development. In this purpose-specific design, the ultrasound waves generated by a linear array are directed toward a scanning reflector which in turn deflects the waves toward the target. In previous experiments, the technical feasibility of this design was demonstrated. Here, the authors are concerned with the minimization of a key design parameter, namely, the array element size, in order to minimize the amount of attenuating/scattering water-equivalent medium that a photon or a electron beam passes through before entering the target. First, the SURLAS design is described. Second, an acoustic model to compute power deposition patterns is presented. This model is coupled to a bioheat transfer model for computation of temperature fields. Third, an analysis is performed to determine the minimum array element size for three target categories. Finally, acoustic fields and temperature distributions induced by the SURLAS for the three target categories are presented. The analysis and simulations show that the SURLAS has the potential to induce uniform temperature distributions in large superficial volumes with small enough elements to allow simultaneous delivery with electron beam therapy.
机译:热疗和电离辐射的同时输送有可能改善临床结果。为此,目前正在开发一种扫描超声反射器-线性阵列系统(SURLAS),该系统既具有使功率适应表层体积又可以与医用线性加速器同时运行的能力。在这种特定目的的设计中,线性阵列产生的超声波被引向扫描反射器,而扫描反射器又将波偏转向目标。在先前的实验中,已经证明了该设计的技术可行性。在此,作者关注关键设计参数的最小化,即阵列元件的尺寸,以最小化光子或电子束在进入目标之前通过的衰减/散射水等效介质的量。首先,描述SURLAS设计。其次,提出了一种用于计算功率沉积模式的声学模型。该模型与生物传热模型耦合以计算温度场。第三,进行分析以确定三个目标类别的最小数组元素大小。最后,给出了由SURLAS引起的三个目标类别的声场和温度分布。分析和模拟表明,SURLAS具有在足够大的表层体积中诱导均匀温度分布的潜力,并且具有足够小的元素以允许与电子束治疗同时递送。

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