Research progress on chemical composition, pharmacological effects of Forsythia suspensa (Thunb.) Vahl and predictive analysis on Q-marker

摘要

The new quality evaluation system takes?traditional Chinese medicine (TCM) quality markers as its core concept, and lays foundation for the future analysis of the quality markers of Lianqiao ( Forsythia suspensa (Thunb.) Vahl , Abbreviated as “ F. suspensa ” below), in order to establish a F. suspensa quality control and quality traceability system. Lianqiao ( Forsythia suspensa (Thunb.) Vahl , Abbreviated as “ F. suspensa ” below)?is traditional Chinese medicine in China, widely distributed all over the country and also highly rich in resources. The Northwest Territories is a genuine producing area. There are many chemical components in F. suspensa , including lignans, phenylethanolic glycosides, flavonoids, C6-C2 natural alcohols and their glycosides, phenolic acids, terpenes and volatile oils. Among them, lignans and phenylethanolic glycosides are the main active components. Based on the review of chemical components or constituents and main pharmacological activities, according to the definition of quality marker, the components of quality marker of F. suspensa were predicted and analyzed from the aspects of plant genetics and chemical composition, traditional efficacy, traditional medicine, new efficacy, blood entering composition, measurable composition, effective composition in different compatibility, and the influence of storage conditions of extract. Further research on its medicinal active ingredients will provide scientific basis for the evaluation of F. suspensa quality.