Non-pncA Gene-Mutated but Pyrazinamide-Resistant Mycobacterium tuberculosis: Why Is That?

Jim Werngren; Erik Alm; Mikael Mansj?

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Non-pncA Gene-Mutated but Pyrazinamide-Resistant Mycobacterium tuberculosis: Why Is That?

机译：非pncA基因突变但耐吡嗪酰胺的结核分枝杆菌：为什么？

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Pyrazinamide (PZA) is a first-line agent with a clear role in the treatment of both drug-susceptible tuberculosis (TB) and PZA-susceptible multidrug-resistant (MDRPZA-S) TB.

机译：吡嗪酰胺（PZA）是一线药物，在治疗药物敏感性结核病（TB）和PZA敏感性多药耐药性（MDRPZA-S）结核病中均具有明确的作用。

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《Journal of Clinical Microbiology》 |2017年第6期|共8页
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Jim Werngren; Erik Alm; Mikael Mansj?;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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1. Biochemical Characterization and Computational Identification of Mycobacterium tuberculosis Pyrazinamidase in Some Pyrazinamide-Resistant Isolates of Iran [J] . The protein journal . 2015,第3期

机译：伊朗抗吡嗪酰胺类分离物中结核分枝杆菌吡嗪酰胺酶的生化特征和计算鉴定
2. Draft Genome Sequences of Two Pyrazinamide-Resistant Clinical Isolates, Mycobacterium tuberculosis 13-4152 and 13-2459 [J] . D. A. Maslov, K. V. Shur, O. B. Bekker, Genome Announcements . 2015,第4期

机译：两个耐吡嗪酰胺临床分离株结核分枝杆菌13-4152和13-2459的基因组序列草案
3. Epidemiologic Correlates of Pyrazinamide-Resistant Mycobacterium tuberculosis in New York City [J] . Verdugo Dawn, Fallows Dorothy, Ahuja Shama, Antimicrobial agents and chemotherapy. . 2015,第10期

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4. Analysis Of Proteome Response of Mycobacterium smegmatis and Mycobacterium tuberculosis in an Integrated Stress Environment [C] . Prahlad K. Rao, Qingbo Li American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：分枝杆菌和结核分枝杆菌蛋白质组反应分析综合应力环境
5. Drug Resistance in Mycobacterium tuberculosis: An Investigation of Drug Transporter P-Glycoprotein and an Evaluation of Improved Diagnosis of Drug Resistant Tuberculosis in Cameroonian Pulmonary Tuberculosis Patients [D] . Abanda, Ngu Njei 2017

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6. Non-pncA Gene-Mutated but Pyrazinamide-Resistant Mycobacterium tuberculosis: Why Is That? [O] . Jim Werngren, Erik Alm, Mikael Mansjö 2017

机译：非pncA基因突变但耐吡嗪酰胺的结核分枝杆菌：为什么？
7. Esters of pyrazinoic acid are active against pyrazinamide-resistant strains of Mycobacterium tuberculosis and other naturally resistant mycobacteria in vitro and ex vivo within macrophages. [O] . Pires David, Valente Emília, Simoes Marta, 2015

机译：吡嗪酸的酯在体外和在巨噬细胞中对结核分枝杆菌和其他天然抗性分枝杆菌的吡嗪酰胺耐药菌株具有活性。

Non-pncA Gene-Mutated but Pyrazinamide-Resistant Mycobacterium tuberculosis: Why Is That?

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