GeneXpert Captures Unstable Methicillin-Resistant Staphylococcus aureus Prone to Rapidly Losing the mecA Gene

摘要

A cefoxitin-susceptible Staphylococcus aureus strain was identified by the Cepheid GeneXpert as methicillin-resistant S. aureus (MRSA). This strain was highly unstable and rapidly lost SCCmec upon subculturing in vitro, indicating that unstable MRSA is best detected by gene amplification-based methods.