Evaluation of the bioNexia Legionella Test, Including Impact of Incubation Time Extension, for Detection of Legionella pneumophila Serogroup 1 Antigen in Urine

摘要

Legionnaires' disease (LD) is a severe pneumonia caused by Legionella spp., a Gram-negative bacillus found in many environments, including (man-made) aquatic systems and soil. Legionella spp. are responsible for 2 to 15% of all community–acquired pneumonias (1, 2). More than 90% of LD cases are caused by Legionella pneumophila, and 70 to 80% of these belong to serogroup type 1 (3, 4).