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首页> 外文期刊>Journal of Clinical Microbiology >Clinical Evaluation of Multiple Inflammation Biomarkers for Diagnosis and Prognosis for Patients with Systemic Inflammatory Response Syndrome
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Clinical Evaluation of Multiple Inflammation Biomarkers for Diagnosis and Prognosis for Patients with Systemic Inflammatory Response Syndrome

机译:多种炎症生物标志物对系统性炎症反应综合征患者的诊断和预后的临床评价

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摘要

A multiplexed biomarker bundle consisting of nine different inflammation markers was evaluated regarding their diagnostic and prognostic performances in 159 adult systemic inflammatory response syndrome (SIRS) patients enrolled at the emergency department. Fibronectin, interleukin-8 (IL-8), biotin, and neutrophil gelatinase-associated lipocalin (NGAL) were the most robust markers but were not superior to the already established markers IL-6, C-reactive protein (CRP), procalcitonin (PCT), and soluble urokinase plasminogen activator receptor (suPAR).
机译:评估了由9种不同炎症标志物组成的多重生物标志物束对急诊科登记的159名成人系统性炎症反应综合征(SIRS)患者的诊断和预后表现。纤连蛋白,白介素8(IL-8),生物素和中性粒细胞明胶酶相关的脂蛋白(NGAL)是最可靠的标志物,但并不优于已经建立的标志物IL-6,C反应蛋白(CRP),降钙素原( PCT)和可溶性尿激酶纤溶酶原激活剂受体(suPAR)。

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