We describe a central venous catheter-related (Port-A-Cath; Smiths Industries Medical Systems [SIMS] Deltec, Inc., St. Paul, Minn.) infection caused by Rhodotorula glutinis in a 51-year-old man with nasopharyngeal carcinoma. He was treated with fluconazole for 8 weeks and had the catheter removed. Two isolates of R. glutinis recovered from blood specimens (one obtained via peripheral veins and one via the catheter) before administration of fluconazole and one recovered from the removed catheter 17 days after initiation of fluconazole therapy exhibited high-level resistance to fluconazole (MICs, >256 μg/ml). These three isolates were found to belong to a single clone on the basis of identical antibiotypes determined by the E test (PDM Epsilometer; AB Biodisk, Solna, Sweden) and biotypes determined by API ID32 C (bioMerieux, Marcy I'Etoile, France) and their identical random amplified polymorphic DNA patterns.
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机译：我们描述了由 Rhodotorula glutinis 造成的中心静脉导管相关感染（Port-A-Cath; Smiths Industries Medical Systems [SIMS] Deltec，Inc.，St。Paul，明尼苏达州）在51-岁的人患有鼻咽癌。他接受氟康唑治疗8周，并拔下了导管。 R的两个分离株。在开始使用氟康唑之前从血液标本中回收的谷氨酰胺（一种是通过外周静脉获得的，一种是通过导管获得的），在氟康唑治疗开始后的17天从回收的导管中提取出的麸质表现出对氟康唑的高度耐药性（MIC，> 256微克/毫升）。根据E测试（PDM Epsilometer; AB Biodisk，Solna，瑞典）和API ID32 C（bioMerieux，Marcy I'Etoile，法国）确定的相同抗生物型，发现这三个分离物属于单个克隆。及其相同的随机扩增多态性DNA模式。
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