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首页> 外文期刊>Journal of Clinical Microbiology >Comparison of the Western immunoblot assay and a glycoprotein G enzyme immunoassay for detection of serum antibodies to herpes simplex virus type 2 in patients with AIDS.
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Comparison of the Western immunoblot assay and a glycoprotein G enzyme immunoassay for detection of serum antibodies to herpes simplex virus type 2 in patients with AIDS.

机译:比较Western免疫印迹测定法和糖蛋白G酶免疫测定法检测AIDS患者2型单纯疱疹病毒血清抗体的方法。

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摘要

Herpes simplex virus type 2 (HSV-2) seroprevalence in 68 patients with AIDS was 77% by Western blot (immunoblot) and 44% by glycoprotein G-2 immunoassay. Each of 16 patients with culture-proven HSV-2 infection was positive by Western blot versus 8 by glycoprotein G-2 immunoassay. No differences in age, race, duration of AIDS, acyclovir usage, or HSV-1 seroprevalence were found to explain differences in sensitivity.
机译:Western blot(免疫印迹)检测68例艾滋病患者的2型单纯疱疹病毒(HSV-2)血清阳性率,糖蛋白G-2免疫检测结果为44%。 Western blot检测16例经培养证实的HSV-2感染的患者中阳性,糖蛋白G-2免疫检测法中的8例为阳性。没有发现年龄,种族,艾滋病持续时间,使用阿昔洛韦或HSV-1血清阳性的差异可以解释敏感性的差异。

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