DNA Fingerprinting of Single Colonies ofHelicobacter pylori from Gastric Cancer Patients Suggests Infection with a Single Predominant Strain

摘要

In each of six gastric cancer patients, repetitive extragenic palindromic PCR DNA fingerprints of 18 single colonies ofHelicobacter pylori from the gastric antrum, corpus, and cardia were identical and matched that of the parental isolate. In three additional gastric cancer patients, 17 of 18 single-colony DNA fingerprints were identical to each other and to the DNA fingerprint of the corresponding parental isolate.