Taurocholate, desoxycholate, and cholate stimulated germination of Clostridium difficile spores in broth medium and enhanced recovery of C. difficile spores on a selective agar medium. Desoxycholate and some crude taurocholate preparations also inhibited multiplication of vegetative cells. At a concentration of 1.2 X 10(-2) M, sodium cholate inhibited multiplication of vegetative cells, but at concentrations of 1.2 X 10(-3) to 2.4 X 10(-3) M, it stimulated germination without inhibiting cell multiplication. Thus, pure sodium taurocholate and sodium cholate may effectively be incorporated in cefoxitin-cycloserine-fructose agar, whereas some crude preparations of sodium taurocholate decrease recovery on this medium.
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机译：牛磺胆酸盐，脱氧胆酸盐和胆酸盐刺激肉汤培养基中艰难梭菌孢子的萌发，并提高了选择性琼脂培养基上艰难梭菌孢子的回收率。脱氧胆酸盐和一些粗牛磺胆酸盐制剂也抑制营养细胞的增殖。在1.2 X 10（-2）M的浓度下，胆酸钠抑制营养细胞的繁殖，但是在1.2 X 10（-3）到2.4 X 10（-3）M的浓度下，它刺激发芽而不抑制细胞的繁殖。因此，可以将纯牛磺胆酸钠和胆酸钠有效地掺入头孢西丁-环丝氨酸-果糖琼脂中，而某些牛磺胆酸钠粗制品会降低这种培养基的回收率。
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