Determination of Triclocarban, Triclosan and Methyl-Triclosan in Environmental Water by Silicon Dioxide/Polystyrene Composite Microspheres Solid-Phase Extraction Combined with HPLC-ESI-MS

摘要

This paper developed asensitive and efficient analytical method for triclocarban (TCC), triclosan(TCS) and Methyl-triclosan (MTCS) determination in environmental water, whichinvolves enrichment by using silicon dioxide/polystyrene composite microspheressolid-phase extraction and detection with HPLC-ESI-MS. The influence of several operationalparameters, including the eluant and its volume, the flow rate and acidity ofwater sample were investigated and optimized. Under the optimum conditions, thelimits of detection were 1.0 ng/L, 2.5 and 4.5 ng/L for TCC, TCS, and MTCS,respectively. The linearity of the method was observed in the range of 5-2000 ng/L, withcorrelation coefficients (r2) >.99. The spiked recoveries of TCC, TCS and MTCS inwater sampleswereachieved in the rangeof 89.5% -96.8% with RSD below5.7%. The proposed method has been successfully applied to analyze real watersamples and satisfactory results were achieved.