Factors of Local Recurrence in Soft Tissue Sarcomas at Yalgado Ouedraogo University Hospital (Burkina Faso)

摘要

Soft tissue sarcomas are characterized by their great anatomo-clinical diversity and their high potential for recurrence. Our Objective was to determine recurrence factors in soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouedraogo University Hospital from 1st January 2010 to 30th August 2015. This is a cohort retrospective study which concerns patients followed-up for soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouedraogo University Hospital from 1st January 2010 to 30th August 2015. The data were analyzed with Epi-info 7 software. To assess the stability of associations, Pearson's chi square tests or Fisher exact tests were used. A risk α=0.05 was admitted. Fifty-four cases of soft tissue sarcomas were collected and 40 cases included in the study. The frequency of soft tissue sarcomas was 0.03% compared to all cancers in our department. On univariate analysis, recurrences were significantly associated with the tumour resection margin (p=0.014), the operator's qualification (p=0.012), the histologic type (p=0.04) and the recurrence history (p=0.0004). On multivariate analysis, the resection margin remained significantly associated with recurrences (p=0.03). Recurrence factors mostly involved the resection margin, the operator's qualification, the histologic type and the recurrence history. A good mastery of soft tissue sarcomas surgery will significantly reduce recurrence risks.