首页> 外文期刊>Journal of Atrial Fibrillation >Association of left Atrial Fibrosis detected by delayed enhancement magnetic resonance imaging and risk of stroke in patients with Atrial Fibrillation.
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Association of left Atrial Fibrosis detected by delayed enhancement magnetic resonance imaging and risk of stroke in patients with Atrial Fibrillation.

机译:延迟增强磁共振成像检测到的左心房纤维化与房颤患者中风的风险相关。

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Normal 0 false false false /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} This is a review of a recent paper by Daccarett et al (1), investigating LA remodeling, as assessed by magnetic resonance imaging (MRI), as a risk factor for stroke. A major motivation for treatment of atrial fibrillation (AF) is to reduce the risk of stroke, which often arises from emboli formed in the static left atrium (LA). Risk stratification for stroke in AF patients, important because it determines the use of anti-coagulants in patients, is clinically performed using the validated CHADS2 score (based on prior stroke, diabetes, hypertension, advanced age, and congestive heart-failure). However, because of its limited predictive power, patients with low, moderate and high risk CHADS2 scores are often prescribed anti-coagulants in equal frequencies (2). There is growing evidence that the burden of AF (i.e. the amount of time that patient remains in AF rhythm) may be a predictor of stroke (3), since during this time emboli can form in the LA appendage (4).
机译:正常0假假假/ *样式定义* / table.MsoNormalTable {mso-style-name:“ Table Normal ”; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:是; mso-style-parent:“ ”; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso分页:寡妇孤儿;字体大小:10.0pt; font-family:“ Times New Roman ”; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}这是Daccarett等人(1)最近发表的一篇论文的综述,该论文研究了通过磁共振成像(MRI)评估的LA重塑作为中风的危险因素。治疗房颤(AF)的主要动机是降低中风的风险,这通常是由静态左心房(LA)中形成的栓子引起的。在房颤患者中风的风险分层很重要,因为它决定了患者是否使用抗凝剂,临床上是使用经过验证的CHADS 2 评分(基于既往中风,糖尿病,高血压,高龄,和充血性心力衰竭)。但是,由于其预测力有限,低,中和高风险CHADS 2 评分的患者经常被处方抗凝剂,频率均等(2)。越来越多的证据表明,房颤的负担(即患者保持房颤节律的时间)可能是中风的预兆(3),因为在这段时间内,栓塞可能会在左心耳附件中形成(4)。

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