A 54-year-old, lightly pigmented woman of African, Indian, and Caucasian descent was noted to have a bluish discoloration of her sclera on routine examination by her optometrist. She was seen by a rheumatologist, who referred her to the ophthalmology service for evaluation of possible bilateral scleromalacia. At presentation, the patient noted an asymptomatic, nonprogressive, bluish discoloration of her sclerae for over 10 years. She had a history of osteoarthritis in her knees and wrists. Her current medications included a multivitamin, glucosamine, and a calcium supplement. She had a 10-year history of tetracycline use (over 1825 grams total) followed by an additional 20 years of minocycline use (1460 grams total) for acne. She had discontinued minocycline 2 years prior to presentation.
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