Chromosomal localization of three GGA4 genes using BAC‐based FISH mapping: a region of conserved synteny between the chicken and human genomes

摘要

The chicken homologues of three genes spaced widely on HSA4q, ANXA5 (annexin A5), ALB (albumin) and EDNRA (endothelin receptor type-A) have been mapped to the GGA4 linkage map but with some uncertainty as to their relative location (Schmid et al. 2000; Suchyta et al. 2001). A cytogenetic map assignment has been made only for the ALB gene (Suzuki et al. 1999). Here we report the chromosomal localization of all three genes on GGA4 by fluorescence in situ hybridization (FISH) using BAC clones as probes.