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Estimating the Cost of Type 1 Diabetes in the U.S.: A Propensity Score Matching Method

机译:估算美国1型糖尿病的费用:倾向得分匹配方法

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Background Diabetes costs represent a large burden to both patients and the health care system. However, few studies that examine the economic consequences of diabetes have distinguished between the two major forms, type 1 and type 2 diabetes, despite differences in underlying pathologies. Combining the two diseases implies that there is no difference between the costs of type 1 and type 2 diabetes to a patient. In this study, we examine the costs of type 1 diabetes, which is often overlooked due to the larger population of type 2 patients, and compare them to the estimated costs of diabetes reported in the literature. Methodology/Principal Findings Using a nationally representative dataset, we estimate yearly and lifetime medical and indirect costs of type 1 diabetes by implementing a matching method to compare a patient with type 1 diabetes to a similar individual without the disease. We find that each year type 1 diabetes costs this country $14.4 billion (11.5–17.3) in medical costs and lost income. In terms of lost income, type 1 patients incur a disproportionate share of type 1 and type 2 costs. Further, if the disease were eliminated by therapeutic intervention, an estimated $10.6 billion (7.2–14.0) incurred by a new cohort and $422.9 billion (327.2–519.4) incurred by the existing number of type 1 diabetic patients over their lifetime would be avoided. Conclusions/Significance We find that the costs attributed to type 1 diabetes are disproportionately higher than the number of type 1 patients compared with type 2 patients, suggesting that combining the two diseases when estimating costs is not appropriate. This study and another recent contribution provides a necessary first step in estimating the substantial costs of type 1 diabetes on the U.S.
机译:背景技术糖尿病费用对患者和医疗保健系统均构成沉重负担。然而,尽管基础病理有所不同,但很少有研究检查糖尿病的经济后果的研究将1型和2型糖尿病这两种主要形式区分开。两种疾病的合并意味着对患者的1型和2型糖尿病的花费没有差异。在这项研究中,我们检查了由于2型患者人数众多而经常被忽视的1型糖尿病的费用,并将它们与文献中报道的估计的糖尿病费用进行比较。方法/主要发现使用全国代表性的数据集,我们通过实施匹配方法将1型糖尿病患者与没有该疾病的相似个体进行比较,估算1型糖尿病的年度和终生医疗费用和间接费用。我们发现,每年1型糖尿病在该国造成的医疗费用和收入损失高达144亿美元(11.5-17.3)。就收入损失而言,1型患者承担的1型和2型费用所占比例不成比例。此外,如果通过治疗干预消除了该病,则可以避免新队列产生的106亿美元(7.2-14.0)和现有1型糖尿病患者一生中的4229亿美元(327.2-519.4)。结论/意义我们发现,与2型患者相比,归因于1型糖尿病的费用比1型患者的数量高得多,这表明在估算费用时将两种疾病合并是不合适的。这项研究和最近的另一项贡献为估算美国1型糖尿病的实质成本提供了必要的第一步。

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