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首页> 外文期刊>International Research Journal of Pure and Applied Chemistry >Cyclic Voltammetric Study of LosartanPotassium
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Cyclic Voltammetric Study of LosartanPotassium

机译:氯沙坦钾的循环伏安法研究

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Cyclic voltammetric technique has been used for investigation of electrochemical parameters of antihypertensive drug, Losartan Potassium. This drug is usually used for the treatment of blood pressure, type II diabetic disease with proteinuria and stroke prevention. In this study Britton Robinson buffer was used as supporting electrolyte at room temperature30±1oC and peak potential (Epc), Peak current(Ipc), transfer coefficient (α) and diffusion coefficient (D) were estimated at different scan rates, pH and concentration. The electrochemical process was found to be adsorption controlled and irreversible. Furthermore, Losartan Potassium represents transfer of two electrons during reduction reaction.
机译:循环伏安法已用于研究降压药氯沙坦钾的电化学参数。该药物通常用于治疗血压,II型糖尿病伴蛋白尿和预防中风。在这项研究中,使用Britton Robinson缓冲液在室温30±1oC下作为支持电解质,并在不同扫描速率,pH和浓度下估算了峰值电势(Epc),峰值电流(Ipc),转移系数(α)和扩散系数(D) 。发现电化学过程是受吸附控制的并且是不可逆的。此外,氯沙坦钾代表还原反应过程中两个电子的转移。

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