In vitro Bioactivity of Polycaprolactone/Bioglass Composites

摘要

A series of Polycaprolactone and Bioglass in the 85SiO₂-10CaO-5P2O₅ (mol. %) systems were synthesized at different quantity of the organic/inorganic components. The 85S Bioglass was prepared via sol-gel method. It was added to the Polycaprolactone matrix at 20, 50 and 80 weight (wt.) %, respectively. In vitro bioactivity of the prepared composites was evaluated in 1.5 Simulated Body Fluid (1.5 SBF). The obtained composite materials before and after static in vitro test were characterized by FTIR and SEM. The obtained experimental data proved that the synthesized composites exhibit good in vitro bioactivity. After immersion in 1.5SBF, SEM depicts the presence of nano-needle-like hydroxyapatite on the immersed 20PCL/80BG and 50PCL/50BG samples.