Thermodynamic study of different substituted imidazolinone drugs at different concentration in 70% (DMF+water) solvent by viscometrically

摘要

In the present work we investigate the densities, specific viscosities of different substituted 5-oxo imidazolinone drugs of different concentration in the range (1x10-2 M to 6x10-4 M) in 70% (DMF+water) solvent at 303K. The experimental data study the effect of concentration of solute on viscosity in DMF-water mixtures. From the viscometric data, the molecular interactions present in different solutions were studied. Appreciable molecular interactions have been observed between solute substituted 5-oxo imidazolinone and solvent 70%(DMF-water) mixture. The themodynamic properties such as free energy change(ΔG), enthalpy change(ΔH) and entropy change (ΔS) of different substituted oxoimidazolinone drugs have been investigated in 70% (DMF+water) solvent by the measurement of densities and viscosities at different temperature such as 305K, 307K and 309K. The experimental data study gives the idea about effect of temperature on the molecular interaction and nature of reaction.