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Pregnancy and Perinatal Outcomes Associated with Acinetobacter baumannii Infection

机译:鲍曼不动杆菌感染的妊娠和围产期结局

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Objective?To determine perinatal and pregnancy outcomes of Acinetobacter baumannii infection using clinicopathologic material from pregnant women, neonates, and perinatal postmortem examinations with positive cultures.Study Design?This is a retrospective record review with placental and postmortem examination.Results?During a 5-year period, 40 positive cultures were found. Three pregnancies with positive cultures close in the peripartum period were all associated with adverse outcomes including spontaneous abortion, preterm labor, and one full-term birth with histological chorioamnionitis. Two positive cultures were found in preterm neonates in the neonatal intensive care unit. Two of three cases of perinatal death grew pure cultures from blood and/or fetal tissue with placental or fetal examination demonstrating evidence of infection/inflammation with fetal inflammatory response.Conclusion?This is the first case series report of A. baumannii-positive cultures in maternal, fetal, and neonatal specimen, with histopathologic evidence of infection. The results suggest a significant role of A. baumannii infection in adverse pregnancy and perinatal outcomes.
机译:目的?使用孕妇,新生儿和围产期尸检,阳性培养的临床病理材料确定鲍曼不动杆菌感染的围产期和妊娠结局研究设计?这是一项回顾性记录,包括胎盘和尸检结果。一年的时间里,发现了40种阳性培养物。围产期三例妊娠合并阳性的妊娠均与不良结局有关,包括自然流产,早产和一例足月出生的组织学绒毛膜羊膜炎。在新生儿重症监护病房的早产儿中发现了两种阳性培养物。在三例围产期死亡病例中,有两例来自血液和/或胎儿组织的纯培养物,经过胎盘或胎儿检查,证明有感染/炎症并伴有胎儿炎症反应。母亲,胎儿和新生儿标本,具有感染的组织病理学证据。结果表明鲍曼不动杆菌感染在不良妊娠和围产期结局中具有重要作用。

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