Antioxidant and tyrosinase inhibitor from Leucaena leucocephala

摘要

The experimental design is divided into two parts: chemical analysis and bioactive assay. One antioxidant lupeol (4) and one inhibition of tyrosinase pheophorbide a methyl ester (7) were identified in?Leucaena leucocephala. Both showed effective 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity compared with vitamin C, and mushroom tyrosinase compared with kojic acid. These results suggest that these constituents of?L. leucocephala?act as natural antioxidants and play a potential role in prevention of pigmentation.