Biomechanical analysis of the interaction phenomena between artificial urinary sphincter and urethral duct

摘要

Male urinary incontinence is a widespread healthcare problem, leading to a miserable quality of life. Artificial urinary sphincter (AUS) is a device inserted mostly around the urethra in adult males, which mimics the urinary sphincter by providing a closure during urinary storage and a subsequent open to permit voiding. The interaction phenomena occurring between AUS cuff and urethral duct represent a fundamental problem in the investigation of AUS reliability and durability. In this work, computational methods are exploited to deeply investigate the mechanics of interaction phenomena occurring between urethral duct and AUS device. Experimental studies are performed on urethral tissues, and structural tests are carried out on the overall urethral duct to obtain a large set of information required for mechanical properties definition. The mechanical behavior of AUS cuff is investigated using mechanical and physicochemical procedures. The cuff conformation is acquired by computed tomography techniques for the definition of the numerical model. Numerical analyses are developed to evaluate the mechanical response of urethral duct in interaction with AUS cuff, considering the lumen occlusion process for maintaining urinary continence. Finally, the investigation of the compressive stress and strain fields within urethral tissues allows the identification of device performance and reliability in correlation with surgical practice.