Estudio de disolucion de comprimidos de bromazepan

摘要

A validated design of the dissolution test was carried out, such test included the Q acceptance applicable to the quality con- trol of Bromazepam tablets. The dissolution characteristics of the Bro- Mazepam tablets of 3,6 and 12 mg be- Longing to 16 laboratories which supply The domestic market were studied with This method, using 500 ml distilled water As a dissolution media, which according To the drug solubility allows to fulfill sink Conditions. The degasification was carried out using The sonicated method. Two assays were made at the same time With the apparaturs I and II of USP at 100 r.p.m afterwards an spectrophotometric quantification of dissolved active princi- ple took place.