Sources of systematic bias in the measurement of water by the coulometric and volumetric karl fischer methods

摘要

The Sources of systematic bias in the measurement of moisture by the volumetric and coulometric karl fischer methods were assessed. using water-saturated octanol as a moisture standard, the measurement accuracy of five coulometric instruments was evaluated. Six possible sources of systematic bias were examined: accuracy of the moisture standard, nonadjustable instrumental bias, operator-adjustable instrumental bias, solvent composi- tion, cell design, and sample composition.