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Nanomaterials: certain aspects of application risk assessment and risk communication

机译:纳米材料:应用风险评估和风险沟通的某些方面

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摘要

Development and market introduction of new nanomaterials trigger the need for an adequate risk assessment of such products alongside suitable risk communication measures. Current application of classical and new nanomaterials is analyzed in context of regulatory requirements and standardization for chemicals, food and consumer products. The challenges of nanomaterial characterization as the main bottleneck of risk assessment and regulation are presented. In some areas, e.g., quantification of nanomaterials within complex matrices, the establishment and adaptation of analytical techniques such as laser ablation inductively coupled plasma mass spectrometry and others are potentially suited to meet the requirements. As an example, we here provide an approach for the reliable characterization of human exposure to nanomaterials resulting from food packaging. Furthermore, results of nanomaterial toxicity and ecotoxicity testing are discussed, with concluding key criteria such as solubility and fiber rigidity as important parameters to be considered in material development and regulation. Although an analysis of the public opinion has revealed a distinguished rating depending on the particular field of application, a rather positive perception of nanotechnology could be ascertained for the German public in general. An improvement of material characterization in both toxicological testing as well as end-product control was concluded as being the main obstacle to ensure not only safe use of materials, but also wide acceptance of this and any novel technology in the general public.
机译:新纳米材料的开发和市场引入引发了对此类产品进行适当风险评估以及适当风险通报措施的需求。在化学品,食品和消费品的法规要求和标准化的背景下,对经典和新型纳米材料的当前应用进行了分析。提出了纳米材料表征作为风险评估和监管的主要瓶颈的挑战。在某些领域,例如,复杂基质中纳米材料的定量,诸如激光烧蚀电感耦合等离子体质谱法之类的分析技术的建立和适应,以及其他可能符合要求的技术。作为示例,我们在此提供一种可靠表征人类暴露于食品包装所产生的纳米材料的方法。此外,还讨论了纳米材料毒性和生态毒性测试的结果,并得出了诸如溶解度和纤维刚性等关键标准作为材料开发和监管中要考虑的重要参数。尽管对公众舆论的分析显示,取决于特定的应用领域,其评级是杰出的,但总体而言,德国公众仍可以肯定纳米技术的正面评价。结论是,毒理学测试和最终产品控制中材料表征的改进是确保不仅安全使用材料,而且还确保该技术和任何新技术在公众中广泛接受的主要障碍。

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