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COVID‐19: Emergence of Infectious Diseases Nanotechnology Aspects Challenges and Future Perspectives

机译:COVID-19:传染病的出现纳米技术方面挑战和未来展望

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摘要

Wuhan, a city of China, is the epicenter for the pandemic outbreak of coronavirus disease‐2019 (COVID‐19). It has become a severe public health challenge to the world and established a public health emergency of international worry. This infectious disease has pulled down the economy of almost all top developed nations. The coronaviruses (CoVs) known for various epidemics caused time to time. Infectious diseases such as severe acute respiratory syndrome (SARS) and middle east respiratory syndrome (MERS), followed by COVID‐19, are all coronaviruses led outbreaks that scourged the history of mankind. CoVs evolved themselves to more infectious, transmissible, and more pandemic with time. To prevent the spread of the SARS‐CoV‐2, many countries have ordered the complete lockdown to combat the outbreak. This paper briefly discussed the historical background of CoVs and the evolution of human coronaviruses (HCoVs), the case studies and the development of their antiviral medications. The viral infection encountered with present‐day challenges and futuristic approaches with the help of nanotechnology to minimize the spread of infectious viruses. The antiviral drugs and their clinical advances, along with herbal medicines for viral inhibition and immunity boosters, are described. Elaboration of tables related to CoVs for the compilation of the literature has been adopted for the better understanding.
机译:武汉是中国的一个城市,是2019年冠状病毒病(COVID-19)大流行爆发的中心。它已成为对世界的严峻公共卫生挑战,并建立了引起国际关注的紧急公共卫生事件。这种传染病已经拖垮了几乎所有最发达国家的经济。因各种流行病而闻名的冠状病毒(CoVs)有时会引起问题。严重急性呼吸道综合症(SARS)和中东呼吸综合症(MERS)等传染病,其次是COVID-19,都是冠状病毒导致的暴发,侵害了人类的历史。 CoV随着时间的流逝逐渐发展为更具传染性,传染性和流行性。为了防止SARS-CoV-2的传播,许多国家/地区已下令全面封锁以抵抗爆发。本文简要讨论了冠状病毒的历史背景和人类冠状病毒(HCoV)的进化,案例研究及其抗病毒药物的发展。在纳米技术的帮助下,病毒感染面临着当今的挑战和未来方法,以最大程度地减少传染性病毒的传播。描述了抗病毒药物及其临床进展,以及用于抑制病毒和增强免疫力的草药。为了更好地理解,已经采用了与CoV相关的表格来进行文献汇编。

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