首页> 美国卫生研究院文献>Aging (Albany NY) >KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling pathway

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KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling pathway

机译：KIF20A通过调节JAK / STAT3信号通路促进大肠癌的细胞恶性行为并增强对化学疗法的抵抗力

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Background/Aims: Kinesin family member 20A (KIF20A) is upregulated in multiple cancers and plays important roles in promoting malignant behavior, whereas its exact role in CRC remains unknown.

机译：背景/目的：Kinesin家族成员20A（KIF20A）在多种癌症中上调，在促进恶性行为中起重要作用，而其在CRC中的确切作用仍然未知。

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期刊名称 Aging (Albany NY)
作者
Man Xiong; Kangmin Zhuang; Yunchen Luo; Qiuhua Lai; Xiaobei Luo; Yuxin Fang; Yue Zhang; Aimin Li; Side Liu;
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作者单位

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年(卷),期 2019(11),24
年度 2019
页码 -1
总页数 17
原文格式 PDF
正文语种
中图分类细胞生物学;
关键词
colorectal cancer; KIF20A; malignant characteristics; JAK/STAT3; chemotherapy resistance;

机译：大肠癌;KIF20A;恶性特征;JAK / STAT3;化疗耐药;

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专利

1. KIF20A Predicts Poor Survival of Patients and Promotes Colorectal Cancer Tumor Progression through the JAK/STAT3 Signaling Pathway [J] . Qi Zhang, Jun Di, Zhiyu Ji, Disease markers . 2020,第2a3期

机译：KIF20A预测患者的差，通过JAK / Stat3信号传导途径促进结肠直肠癌肿瘤进展
2. FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway [J] . Li Piao, Huang Tingting, Zou Qi, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2019,第10期

机译：FGFR2通过Jak / Stat3信号通路促进结肠直肠癌中PD-L1的表达
3. B7-H3 promotes cell migration and invasion through the Jak2/Stat3/MMP9 signaling pathway in colorectal cancer [J] . Liu Fen, Zhang Ting, Zou Shitao, Molecular medicine reports . 2015,第4aPta1期

机译：B7-H3通过Jak2 / Stat3 / MMP9信号通路促进结直肠癌中的细胞迁移和侵袭
4. The molecular regulation of the malignant progression of human colorectal cancer [C] . A. JUN Falk Symposium . 2006

机译：人结肠直肠癌恶性进展的分子调节
5. Pharmacological Evaluation of Cellular Chemotherapy Resistance in Cancer Cells Via Lipid Pathway Related Mechanisms [D] . Alarmouti, Hanin Ahmad. 2021

机译：通过脂质途径相关机制对癌细胞中细胞化疗抗性的药理评估
6. KIF20A Predicts Poor Survival of Patients and Promotes Colorectal Cancer Tumor Progression through the JAK/STAT3 Signaling Pathway [O] . Qi Zhang, Jun Di, Zhiyu Ji, 2020

机译：KIF20A预测患者的差通过JAK / Stat3信号传导途径促进结肠直肠癌肿瘤进展
7. KIF20A Predicts Poor Survival of Patients and Promotes Colorectal Cancer Tumor Progression through the JAK/STAT3 Signaling Pathway [O] . Qi Zhang, Jun Di, Zhiyu Ji, 2020

机译：KIF20A预测患者的差，通过JAK / Stat3信号传导途径促进结肠直肠癌肿瘤进展

KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling pathway

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