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Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells

机译：载有阿霉素的Pluronic P123修饰的纳米胶束增强了对耐药性乳腺癌细胞的抑瘤作用

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Objective: Nano micelles (NMs) have been widely used for various biomedical applications due to its unique physiochemical properties. This study aimed to investigated the anti-tumor effect of doxorubicin (Dox)-loaded Pluronic P123 (P123) and PEG2000-DSPE mixed NMs in drug-resistant breast cancer cells.

机译：目的：纳米胶束（NMs）由于其独特的物理化学特性已被广泛用于各种生物医学应用。这项研究旨在研究阿霉素（Dox）负载的Pluronic P123（P123）和PEG2000-DSPE混合NM在抗药性乳腺癌细胞中的抗肿瘤作用。

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期刊名称 Aging (Albany NY)
作者
Xiaoyu Zhang; Weibin Chen; Jie Bai; Lijun Jin; Xiaoning Kang; Hui Zhang; Zunyi Wang;
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作者单位

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年(卷),期 2020(12),9
年度 2020
页码 -1
总页数 12
原文格式 PDF
正文语种
中图分类细胞生物学;
关键词
nano micelles; multi-drug resistance; breast cancer; P-glycoprotein; Pluronic P123 modification;

机译：纳米胶束;多药耐药性;乳腺癌;P-糖蛋白;Pluronic P123修饰;

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专利

1. Enhanced antitumor efficacy by paclitaxel-loaded pluronic P123/F127 mixed micelles against non-small cell lung cancer based on passive tumor targeting and modulation of drug resistance. [J] . Zhang W, Shi Y, Chen Y, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2010,第3期

机译：装载紫杉醇的普鲁尼克P123 / F127混合胶束可基于被动肿瘤靶向和耐药性调节增强对非小细胞肺癌的抗肿瘤功效。
2. Biotin-targeted Pluronic (R) P123/F127 mixed micelles delivering niclosamide: A repositioning strategy to treat drug-resistant lung cancer cells [J] . Russo Annapina, Pellosi Diogo Silva, Pagliara Valentina, International Journal of Pharmaceutics . 2016,第1期

机译：靶向生物素的Pluronic（R）P123 / F127混合胶束传递神经酰胺：治疗耐药性肺癌细胞的重新定位策略
3. Biotin-targeted Pluronic (R) P123/F127 mixed micelles delivering niclosamide: A repositioning strategy to treat drug-resistant lung cancer cells [J] . Russo Annapina, Pellosi Diogo Silva, Pagliara Valentina, International Journal of Pharmaceutics . 2016,第1期

机译：靶向生物素的Pluronic（R）P123 / F127混合胶束传递神经酰胺：治疗耐药性肺癌细胞的重新定位策略
4. Paclitaxel-Loaded Micelles Modified with MCF-7 Cell-Specific Phage Protein: Enhance Selective Binding to Target Cancer Cells and Increased Cytotoxicity [C] . Tao Wang, Avni Clerk, Valery A Petrenko, Annual meeting exposition of the Controlled Release Society . 2010

机译：载有紫杉醇的胶束用MCF-7细胞特异性噬菌体蛋白修饰：增强对靶癌细胞的选择性结合并增加细胞毒性
5. Doxorubicin-Nanocarriers Enhance Doxorubicin Uptake and Clathrin-Mediated Endocytosis in Drug-Resistant Ovarian Cancer Cells. [D] . Arora, Hans Chin. 2012

机译：阿霉素纳米载体增强了抗药性卵巢癌细胞中阿霉素的摄取和网格蛋白介导的内吞作用。
6. PCM-17INTRATUMOURAL CONVECTION ENHANCED DELIVERY OF LBH589 (PANOBINOSTAT) LOADED PLURONIC-P407 NANO-MICELLES IS ASSOCIATED WITH ENHANCED SURVIVAL AND ANTI-TUMOUR RESPONSE IN THE ORTHOTOPIC F98/FISCHER 344 RAT GLIOMA MODEL [O] . William G.B. Singleton, Alison S. Bienemann, Clare L. Killick-Cole, 2016

机译：LBH589（PANOBINOSTAT）装载的PLURONIC-P407纳米胶束的PCM-17体腔内对流增强传递与正交F98 / FISCHER 344 RAT胶质瘤模型中增强的生存力和抗肿瘤反应有关
7. Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells [O] . Xiaoyu Zhang, Weibin Chen, Jie Bai, 2020

机译：PLURONIC P123改性纳米胶束加载多柔比星的肿瘤抑制效应，对耐药乳腺癌细胞增强了肿瘤抑制作用
8. Synergistic Cytotoxicity of Human Breast Cancer Cells by a Novel Nano- Particle Based Delivery of Ceramide With Paclitaxel and/or Doxorubicin [R] . Mehta, S. 2004

机译：基于纳米粒子的神经酰胺与紫杉醇和/或多柔比星递送的人乳腺癌细胞的协同细胞毒性

Pluronic P123 modified nano micelles loaded with doxorubicin enhanced tumor-suppressing effect on drug-resistant breast cancer cells

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