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Preclinical combination of TP-0903 an AXL inhibitor and B-PAC-1 a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia

机译：TP-0903（一种AXL抑制剂）和B-PAC-1（一种促胰蛋白酶活性的化合物）与依鲁替尼的临床前组合在慢性淋巴细胞性白血病中的应用

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Viralkumar Patel; Michael J. Keating; William G. Wierda; Varsha Gandhi;
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年(卷),期 -1(57),6
年度 -1
页码 1494–1497
总页数 7
原文格式 PDF
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1. 在乳腺癌中应用CRISPR/Cas9筛选发现一种动粒-微管依赖的Aurora-A抑制剂耐药机制 [J] . 陈艾琳, 林永辉, 王自峰, 癌症（英文版） . 2021,第008期
2. Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia [J] . Patel Viralkumar, Keating Michael J., Wierda William G., Leukemia and lymphoma . 2016,第6期

机译：TP-0903（一种AXL抑制剂）和B-PAC-1（一种促胰蛋白酶活性的化合物）与依鲁替尼的临床前组合在慢性淋巴细胞性白血病中的应用
3. Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors [J] . Sinha Sutapa, Boysen Justin, Nelson Michael, Clinical cancer research: an official journal of the American Association for Cancer Research . 2015,第9期

机译：有针对性的Axl抑制引发慢性淋巴细胞性白血病B细胞凋亡，并与BTK抑制剂组合显示协同/加和作用
4. Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors [J] . Sinha Sutapa, Boysen Justin, Nelson Michael, Clinical cancer research: an official journal of the American Association for Cancer Research . 2015,第9期

机译：靶向AXL抑制将慢性淋巴细胞白血病B细胞凋亡，并表现出与BTK抑制剂组合的协同/添加剂效应
5. Proteomics-based target deconvolution of clinical multi-kinase inhibitors inducing apoptosis in primary chronic lymphocytic leukemia cells (CLL) [C] . Marcus Bantscheff, Ulrich Kruse, Christian P. Pallasch, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：基于蛋白质组学的临床多激酶抑制剂诱导肾凋亡凋亡的靶碎屑（CLL）
6. Kinase Targeting Therapies in Chronic Lymphocytic Leukemia: Mechanisms of Acquired Ibrutinib Resistance and the Pre-Clinical Development of OSU-T315. [D] . Liu, Ta-Ming. 2014

机译：激酶靶向疗法在慢性淋巴细胞性白血病中：获得性依鲁替尼耐药性的机制和OSU-T315的临床前开发。
7. Axl Inhibition Primes Chronic Lymphocytic Leukemia B-Cells to Apoptosis and Show Synergistic/Additive Effects in Combination with BTK inhibitors [O] . Sutapa Sinha, Justin Boysen, Michael Nelson, -1

机译：Axl抑制引发慢性淋巴细胞白血病B细胞凋亡并与BTK抑制剂组合显示协同/加和作用
8. Addition of venetoclax at time of progression in ibrutinib‐treated patients with chronic lymphocytic leukemia: Combination therapy to prevent ibrutinib flare [O] . Paul J. Hampel, Timothy G. Call, Wei Ding, 2019

机译：在伊布勒替尼治疗的慢性淋巴细胞白血病患者进展时添加威尼肽：联合疗法，以防止Ibrutinib Flare

Preclinical combination of TP-0903 an AXL inhibitor and B-PAC-1 a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia

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