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Patterned Plasmonic Surfaces—Theory Fabrication and Applications in Biosensing

机译:等离子体等离子表面图案—理论制备及其在生物传感中的应用

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摘要

Low-profile patterned plasmonic surfaces are synergized with a broad class of silicon microstructures to greatly enhance near-field nanoscale imaging, sensing, and energy harvesting coupled with far-field free-space detection. This concept has a clear impact on several key areas of interest for the MEMS community, including but not limited to ultra-compact microsystems for sensitive detection of small number of target molecules, and “surface” devices for optical data storage, micro-imaging and displaying. In this paper, we review the current state-of-the-art in plasmonic theory as well as derive design guidance for plasmonic integration with microsystems, fabrication techniques, and selected applications in biosensing, including refractive-index based label-free biosensing, plasmonic integrated lab-on-chip systems, plasmonic near-field scanning optical microscopy and plasmonics on-chip systems for cellular imaging. This paradigm enables low-profile conformal surfaces on microdevices, rather than bulk material or coatings, which provide clear advantages for physical, chemical and biological-related sensing, imaging, and light harvesting, in addition to easier realization, enhanced flexibility, and tunability.
机译:低轮廓的图案化等离子表面与多种硅微结构协同作用,以大大增强近场纳米级成像,传感和能量收集以及远场自由空间检测。该概念对MEMS社区感兴趣的几个关键领域产生了明显影响,包括但不限于用于灵敏检测少量目标分子的超紧凑微系统以及用于光学数据存储,微成像和光学成像的“表面”设备。显示。在本文中,我们回顾了等离激元理论的最新技术,并推导了有关与微系统,制造技术以及在生物传感中选择应用的等离激元集成的设计指南,包括基于折射率的无标记生物传感,等离激元集成的芯片实验室系统,等离子近场扫描光学显微镜和用于细胞成像的等离子芯片系统。这种范例可以在微型设备上实现低轮廓的共形表面,而不是散装材料或涂层,这为物理,化学和生物相关的感测,成像和光收集提供了明显的优势,此外更易于实现,增强的灵活性和可调性。

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