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Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis

机译:固定数字乳腺断层合成的空间分布多束场发射X射线源的设计与表征

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摘要

Digital breast tomosynthesis (DBT) is a limited angle computed tomography technique that can distinguish tumors from its overlying breast tissues and has potentials for detection of cancers at a smaller size and earlier stage. Current prototype DBT scanners are based on the regular full-field digital mammography systems and require partial isocentric motion of an x-ray tube over certain angular range to record the projection views. This prolongs the scanning time and, in turn, degrades the imaging quality due to motion blur. To mitigate the above limitations, the concept of a stationary DBT (s-DBT) scanner has been recently proposed based on the newly developed spatially distributed multibeam field emission x-ray (MBFEX) source technique using the carbon nanotube. The purpose of this article is to evaluate the performance of the 25-beam MBFEX source array that has been designed and fabricated for the s-DBT system. The s-DBT system records all the projection images by electronically activating the multiple x-ray beams from different viewing angles without any mechanical motion. The configuration of the MBFEX source is close to the published values from the Siemens Mammomat system. The key issues including the x-ray flux, focal spot size, spatial resolution, scanning time, beam-to-beam consistency, and reliability are evaluated using the standard procedures. In this article, the authors describe the design and performance of a distributed x-ray source array specifically designed for the s-DBT system. They evaluate the emission current, current variation, lifetime, and focal spot sizes of the source array. An emission current of up to 18 mA was obtained at 0.5×0.3 mm effective focal spot size. The experimentally measured focal spot sizes are comparable to that of a typical commercial mammography tube without motion blurring. Trade-off between the system spatial resolution, x-ray flux, and scanning time are also discussed. Projection images of a breast phantom were collected using the x-ray source array from 25 different viewing angles without motion. These preliminary results demonstrate the feasibility of the proposed s-DBT scanner. The technology has the potential to increase the resolution and reduce the imaging time for DBT. With the present design of 25 views, they demonstrated experimentally the feasibility of achieving 11 s scanning time at full detector resolution with 0.5×0.3 mm source resolution without motion blur. The flexibility in configuration of the x-ray source array will also allow system designers to consider imaging geometries that are difficult to achieve with the conventional single-source rotating approach.
机译:数字乳腺断层合成(DBT)是一种有限角度计算机断层扫描技术,可以将肿瘤与其上覆的乳腺组织区分开来,并且有潜力在较小规模和早期阶段检测出癌症。当前的原型DBT扫描仪基于常规的全视野数字乳房X线照相系统,并且需要X射线管在一定角度范围内的局部等中心运动以记录投影视图。由于运动模糊,这会延长扫描时间,进而降低成像质量。为了减轻上述限制,最近基于使用碳纳米管的新开发的空间分布多束场发射x射线(MBFEX)源技术,提出了固定式DBT(s-DBT)扫描仪的概念。本文的目的是评估为s-DBT系统设计和制造的25束MBFEX源阵列的性能。 s-DBT系统通过电子激活来自不同视角的多个X射线束来记录所有投影图像,而无需任何机械运动。 MBFEX源的配置接近于西门子Mammomat系统发布的值。使用标准程序评估了关键问题,包括X射线通量,焦点尺寸,空间分辨率,扫描时间,光束与光束的一致性以及可靠性。在本文中,作者描述了专门为s-DBT系统设计的分布式x射线源阵列的设计和性能。他们评估源阵列的发射电流,电流变化,寿命和焦点尺寸。在有效焦点尺寸为0.5×0.3 mm时,可获得高达18 mA的发射电流。实验测得的焦斑大小可与没有运动模糊的典型商用乳腺X射线摄影管相媲美。还讨论了系统空间分辨率,X射线通量和扫描时间之间的权衡。使用X射线源阵列从25个不同的视角不动的情况下收集乳房幻影的投影图像。这些初步结果证明了所提出的s-DBT扫描仪的可行性。该技术具有提高分辨率和减少DBT成像时间的潜力。利用25个视图的当前设计,他们通过实验证明了在全探测器分辨率下以0.5×0.3 mm的源分辨率实现11 s扫描时间而不产生运动模糊的可行性。 X射线源阵列配置的灵活性也将使系统设计人员能够考虑使用常规单源旋转方法难以实现的成像几何形状。

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