Streptococcus pyogenes strains in Sao Paulo Brazil: molecular characterization as a basis for StreptInCor coverage capacity analysis

摘要

BackgroundSeveral human diseases are caused by Streptococcus pyogenes, ranging from common infections to autoimmunity. Characterization of the most prevalent strains worldwide is a useful tool for evaluating the coverage capacity of vaccines under development. In this study, a collection of S. pyogenes strains from Sao Paulo, Brazil, was analyzed to describe the diversity of strains and assess the vaccine coverage capacity of StreptInCor.