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MiR-34a affects dexmedetomidine-inhibited chronic inflammatory visceral pain by targeting to HDAC2

机译：MiR-34a通过靶向HDAC2影响右美托咪定抑制的慢性炎性内脏痛

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BackgroundDexmedetomidine (DEX) has been used as an anesthetic for decades. The present investigation aimed to elucidate the analgesic impact of DEX on 2,4,6-Trinitrobenzenesulfonic acid (TNBS)-induced chronic inflammatory visceral pain (CIVP) in rats.

机译：背景右美托咪定（DEX）被用作麻醉剂已有数十年了。本研究旨在阐明DEX对大鼠2,4,6-三硝基苯磺酸（TNBS）诱导的慢性炎性内脏痛（CIVP）的镇痛作用。

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期刊名称 BMC Anesthesiology
作者
Meng Liang; Aijie Shao; Xinsheng Tang; Meiling Feng; Jing Wang; Yingna Qiu;
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作者单位

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年(卷),期 2019(19),-1
年度 2019
页码 131
总页数 10
原文格式 PDF
正文语种
中图分类麻醉学;麻醉学;
关键词
CIVP DEX miR-34a HDAC Pain behaviors;

机译：CIVP;DEX;miR-34a;HDAC;疼痛行为;

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专利

1. MiR-34a affects dexmedetomidine-inhibited chronic inflammatory visceral pain by targeting to HDAC2 [J] . Meng Liang, Aijie Shao, Xinsheng Tang, BMC Anesthesiology . 2019,第1期

机译：MiR-34a通过靶向HDAC2影响右美托咪定抑制的慢性炎性内脏痛
2. Spinal miR-34a regulates inflammatory pain by targeting SIRT1 in complete Freund's adjuvant mice [J] . Chen Shuangdong, Gu Yixiao, Dai Qinxue, Biochemical and Biophysical Research Communications . 2019,第4期

机译：脊髓miR-34a通过瞄准弗氏佐剂小鼠的刺激性来调节炎症疼痛
3. Moxibustion Eases Chronic Inflammatory Visceral Pain In Rats Via MAPK Signaling Pathway In The Spinal Cord [J] . Yan Huang, Dan Zhang, Zhi-Yuan Li, Journal of Pain Research . 2019,第1期

机译：艾灸通过脊髓中MAPK信号通路缓解大鼠慢性炎症内心疼痛
4. Understanding chronic inflammatory and neuropathic pain [C] . Jane P. Hughes, Iain Chessell, Richard Malamut, Translational Stem Cell Conference . 2012

机译：了解慢性炎症和神经病疼痛
5. Consuming an Anti-Inflammatory Diet to Alleviate Chronic Pain. [D] . Mandolfo, Christina M. 2018

机译：食用抗炎饮食以减轻慢性疼痛。
6. Correction: Regional Neuroplastic Brain Changes in Patients with Chronic Inflammatory and Non-Inflammatory Visceral Pain [O] . 2010

机译：校正：慢性炎性和非炎性内脏痛患者的局部神经增生性脑部改变
7. Regional neuroplastic brain changes in patients with chronic inflammatory and non-inflammatory visceral pain. [O] . Jui-Yang Hong, Jennifer S Labus, Zhiguo Jiang, 2014

机译：慢性炎症性和非炎性内脏痛患者的局部神经塑料脑变化。
8. VIPER: Chronic Pain after Amputation: Inflammatory Mechanisms, Novel Analgesic Pathways, and Improved Patient Safety. [R] . Van de Ven, T. 2017

机译：VIpER：截肢后的慢性疼痛：炎症机制，新的镇痛途径和改善的患者安全性。

MiR-34a affects dexmedetomidine-inhibited chronic inflammatory visceral pain by targeting to HDAC2

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