cqvip:We investigated the value of patch testingwith dandelion (Compositae) extract in addition to sesquiterpene lactone (SL) mix in selected patients. After we detected a case of contact erythema multiforme after patch testing with dandelion and common chickweed (Caryophyllaceae),additional testing with common chickweed extract was performed. A total of 235 adults with a mean age of 52.3 years were tested. There were 66 men and 169 women: 53 consecutive patients with allergic contact dermatitis (ACD); 43 with atopic dermatitis (AD); 90 non-atopics suffering from non-allergic chronic inflammatory skin diseases; 49 healthy volunteers. All were tested with SL mix 0.1%petrolatum (pet.) and diethyl ether extracts from Taraxacum officinale (dandelion) 0.1 and 3.0%pet. and from Stellaria media (common chickweed) 0.1 and 3%pet. A total of 14 individuals (5.9%) showed allergic reaction (AR) to at least 1 of the plant allergens,4 (28.6%) to common chickweed extract,and 11 (78.6%) to Compositae allergens. These 11 persons made the overall prevalence of 4.7%: 8 (3.4%) were SL-positive and 3 (1.3%) reacted to dandelion extract. 5 persons (45.5%) had AD,2 had ACD,2 had psoriasis and 2 were healthy controls. The Compositae allergy was relevant in 8 cases (72.7%). The highest frequency of SL mix sensitivity (9.3%) was among those with AD. Half the SL mix-sensitive individuals had AD. ARs to dandelion extract were obtained only among patients with eczema. A total of 9 irritant reactions (IRs) in 9 individuals (3.8%) were recorded,8 to SL mix and 1 to common chickweed extract 3.0%pet. No IR was recorded to dandelion extract (P=0.007). Among those with relevant Compositae allergy,50.0%had AR to fragrance mix and balsam of Peru (Myroxylon pereirae resin) and colophonium. SLs were detected in dandelion but not in common chickweed. Our study confirmed the importance of 1 positive reaction for emerging,not fully established,Compositae allergy. In conclusion,the overall prevalence of 4.7%in our study represents a basal SL mix detection rate of 3.4%reinforced and safely supplemented by testing with the dandelion extract.
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