Significant Spike-Specific IgG and Neutralizing Antibodies in Mice Induced by a Novel Chimeric Virus-Like Particle Vaccine Candidate for Middle East Respiratory Syndrome Coronavirus

Jiaming Lan12; Yao Deng1; Jingdong Song1; Baoying Huang1; Wenling Wang1; Wenjie Tan1

首页> 中文期刊> 《中国病毒学：英文版》 >Significant Spike-Specific IgG and Neutralizing Antibodies in Mice Induced by a Novel Chimeric Virus-Like Particle Vaccine Candidate for Middle East Respiratory Syndrome Coronavirus

Significant Spike-Specific IgG and Neutralizing Antibodies in Mice Induced by a Novel Chimeric Virus-Like Particle Vaccine Candidate for Middle East Respiratory Syndrome Coronavirus

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Dear Editor, Middle East respiratory syndrome coronavirus (MERSCoV),first isolated in 2012,has emerged zoonotically among humans (van Boheemen et al.2012).Since then, MERS-CoV continues to be a public health concern,with a fatality rate of 35%.On-going MERS-CoV outbreaks highlight the urgent need for the development of interventional measures,including an effective vaccine against MERS-CoV infection.Currently,no licensed therapeutic or vaccine is available (Okba et al.2017).

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《中国病毒学：英文版》 |2018年第5期|P.453-455|共3页
作者
Jiaming Lan12; Yao Deng1; Jingdong Song1; Baoying Huang1; Wenling Wang1; Wenjie Tan1;
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作者单位

[1]MOH Key Laboratory of Medical Virology,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;

[2]Department of Pathogenic Biology,Hebei Medical University,Shijiazhuang 050017,China;

[1]MOH Key Laboratory of Medical Virology,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;

[1]MOH Key Laboratory of Medical Virology,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;

[1]MOH Key Laboratory of Medical Virology,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;

[1]MOH Key Laboratory of Medical Virology,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;

[1]MOH Key Laboratory of Medical Virology,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;

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原文格式 PDF
正文语种 CHI
中图分类生物科学;
关键词
Candidate; IgG;

机译：候选人;IgG;

Significant Spike-Specific IgG and Neutralizing Antibodies in Mice Induced by a Novel Chimeric Virus-Like Particle Vaccine Candidate for Middle East Respiratory Syndrome Coronavirus

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