Identification and genomic analysis of a novel member of Microviridae, IME-16, through high-throughput sequencing

摘要

<正>Dear Editor,Bacteriophages predominate in the biosphere and outnumber their hosts by at least one order of magnitude(Srinivasiah et al.,2008).They have been used for over90 years as an alternative to antibiotics in Eastern Europe(Deresinski,2009).With the increasing emergence of antibiotic resistance,the therapeutic potential of bacteriophages is being reevaluated(Kutter et al.,2010).Until recently,phages possessing ds DNA genomes have been