CRISPR-Cas-like system in giant viruses:why MIMIVIRE is not likely to be an adaptive immune system

摘要

Giant viruses from the Mimiviridae family(Mimivirus,Megavirus,etc.)replicate inside their Acanthamoeba host by the mean of a large intracytoplasmic virion factory within which DNA transcription and replication take place using the virus encoded machineries.Members of the Mimiviridae have been isolated in association with much smaller