The Establishment and Spatiotemporal History of A Novel HIV-1 CRF01_AE Lineage in Shenyang City, Northeastern China in 2002–2019

摘要

Dear Editor,In China,HIV-1 CRF01_AE has always been one of the most prevalent subtypes,especially among sexually active population,since it was initially reported in Yunnan and Guangxi Provinces during the early 1990s(Cheng et al.1994;Yu et al.1998;Chen et al.1999).Multiple independent introductions of CRF01_AE have led to the establishment of at least eight epidemic lineages in China,which have been circulating among different high-risk populations and have variable prevalence and geographic distribution(Li et al.2017).