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急性出血性脑卒中进展及与预后关系的前瞻性研究

         

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目的 探讨急性出血性脑卒中进展及其与预后的关系.方法 前瞻性连续登记237例急性出血性脑卒中患者,根据欧洲进展性卒中研究小组定义的进展性卒中诊断标准判定卒中有无进展,并进行定期随访;采用单因素和多因素Lo0stic回归法分析卒中进展与预后的关系.结果 75例(31.6%)诊断为进展性脑卒中;进展性卒中患者在3,6个月随访时死亡和死亡/残疾比例均高于非进展患者(P<0.05),卒中进展是3个月死亡和死亡/残疾、6个月死亡和死亡/残疾的独立危险因素.结论 急性出血性脑卒中患者中约有30%可出现病情进展,卒中进展是预后不良的独立危险因素.%Objective To analyze the relationship between progressing stroke (PS) and clinical outcomes in intracerebral hemorrhage patients. Methods Acute intracerebral hemorrhage patients ( n = 237) were registered prospectively and consecutively, then whether or not stroke in progress was determined according to the diagnostic criteria defined by European Progressing Stroke Study Group; the patients were followed up, the relationship between PS and outcomes was determined by single factors analysis and multivariate Logistic regression. Results Seventy-five patients (31.6%) were diagnosed as PS; the proportion of death and death/disability was higher in patients with PS than those in patients without PS(P<0.05), PS was independent predictor of death and death/disability at the end of and and 6th month. Conclusions The incidence of PS in intracerebral hemorrhage patients was about 30%, PS is an independent risk factor for the poor prognosis of intracerebral hemorrhage patients.

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