首页> 中文期刊> 《山东医药》 >荞麦花叶发酵醇提物对大鼠餐后血糖的影响及机制探讨

荞麦花叶发酵醇提物对大鼠餐后血糖的影响及机制探讨

         

摘要

Objective To observe the ethanol extracts from fermented leaves of buckwheat flowers ( hereinafter re-ferred to as alcohol extracts ) on postprandial blood glucose in rats and its mechanism .Methods Forty rats were randomly divided into the low-dose, medium-dose and high-dose groups and the control group A (n=10), which were respectively administered by 30, 60 and 120 mg/kg alcohol extracts and purified water .After 20 min, 2.5 g/kg glucose was used for intragastric administration .Meanwhile , the blood glucose was measured at 0 and 60 min.The inhibition rate of blood glu-cose in each group was calculated .We took another 20 rats to kill them to make the everted intestinal sacs .Then we divid-ed the 18 everted intestinal sacs into groups A , B, C, D, E and the control group B , which were respectively placed to 0.5, 1.0, 2.5, 12.5, 25 mg/mL ethanol extracts and purified water .After training for 2 h, we took the liquid within in-testinal sacs to measure the OD value with glucose reagents box and calculated the glucose inhibition rate of each group . Results The blood glucose level at 60 min: the high-dose group

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