Objective To investigate clinical value of inferior vena cava collapsibility index in evaluating negative flu -id balance in septic patients .Methods A prospective observational study was conducted , in which 94 septic patients were enrolled.94 septic patients were divided into positive fluid balance group (47 patients) and negative fluid balance group (47 patients ) .For septic patients , serial echocardiography was performed at 8 am and 8 pm in the first 3 days also after 24 h of negative fluid balance onset , the inferior vena cava collapsibility index was calculated .Results Compared with positive fluid balance group , the inferior vena cava collapsibility index was significantly increased in negative fluid balance group (54.98%±5.78%vs 47.60%±10.98%, P<0.05).The AUC(area under the curve)of ROC predicating onset of neg-ative fluid balance by inferior vena cava collapsibility index was 0.705.The cut off value of the inferior vena cava collaps-ibility index for discrimination of negative fluid balance was determined as 52.79%with sensitivity of 72.3%and specifici-ty of 61.7%.Conclusions The inferior vena cava collapsibility index can evaluate negative fluid balance in septic pa -tients with higher sensitivity than specificity .%目的：探讨下腔静脉塌陷率评估脓毒症患者液体负平衡状态的临床价值。方法选取脓毒症患者94例，3 d内液体平衡状态始终为正平衡47例（正平衡组）、负平衡47例（负平衡组）。患者均接受彩色多普勒超声检查，计算下腔静脉塌陷率。结果正平衡组、负平衡组下腔静脉塌陷率分别为47．60％±10．98％、54．98％±5．78％，两组比较，P＜0．05。下腔静脉塌陷率预测液体负平衡的受试者工作特征曲线下面积为0．705，以下腔静脉塌陷率52．79％为阈值，预测液体负平衡的敏感度为72．3％、特异度为61．7％。结论下腔静脉塌陷率能评估脓毒症患者液体负平衡状态，且敏感度较高。
展开▼
