早期进展性脑梗死的危险因素分析

摘要

Objective To investigate the risk factors for the early progressive cerebral infarction ( EPCI) .Methods The general clinical factors and cerebral infarction related factors were compared between 48 cases of EPCI patients ( EPCI group) and 86 cases of non-progressive cerebral infarction patients ( ACI group) by using retrospective analysis.Subse-quently, the statistically significant indicators from above univariate analysis were analyzed using binary logistic regression analysis.Results Fibrinogen, hypertension, diabetes and cerebral microbleeds were significantly different between these two groups (all P<0.05).Cerebral microbleeds and diabetes were closely related to the progressive cerebral infarction (all P<0.05).Conclusion Cerebral microbleeds and diabetes were the independent risk factors for EPCI.%目的：分析早期进展性脑梗死（ EPCI）的危险因素。方法采用回顾性研究的方法，对48例EPCI患者（ EPCI组）及86例非进展性脑梗死患者（ ACI组）的一般临床因素、脑梗死相关因素进行对比分析，然后将上述两组差异有统计学意义的指标进行二分类logistic多因素回归分析。结果两组血纤维蛋白原水平及高血压、糖尿病、脑微出血例数相比，P均＜0．05；糖尿病、脑微出血与脑梗死的进展密切相关（P均＜0．05）。结论糖尿病及脑微出血是EPCI的独立危险因素。