Objective To investigate the clinical features and influencing factors of prognosis in super - aged patients with posterior circulation ischemic stroke. Methods A total of 82 super - aged patients with posterior circulation ischemic stroke (equal or over 80 years old) were selected in Traditional Chinese Medicine Hospital of Zhangjiagang from 2010 to 2014,and their clinical data was immediately collected after admission,including gender,age,past medical history,symptoms and signs, NIHSS; related influencing factors of prognosis were recorded, including hypertension, diabetes, elevated LDL, hyperhomocysteinemia,coronary heart disease,atrial fibrillation,coronary heart disease,smoking history,drinking history and stroke history. All of the patients were followed up for 3 months,modified Rankin scale was used to evaluate the prognosis,and multivariate Logistic regression analysis was used to analyze the influencing factors of prognosis. Results The main clinical symptoms were dizziness/ vertigo( accounted for 69. 5% ) and weakness of extremities( accounted for 68. 3% ),the main clinical signs were acroparalysis( accounted for 54. 9% ),positive Babinski sign/ Chaddock sign( accounted for 46. 3% ), ataxia(accounted for 43. 9% )and central facial paralysis(accounted for 40. 2% ). After 3 - month fellow - up,56 patients got good prognosis( accounted for 68. 3% ),26 patients got bad prognosis( accounted for 31. 7% ). Multivariate Logistic regression analysis showed that,lower NIHSS at admission〔OR = 2. 648,95% CI(1. 552,4. 463)〕,longer time for seeing a doctor after attack〔 OR = 1. 784,95% CI(1. 142,2. 864)〕,stroke history〔 OR = 4. 402,95% CI(1. 165,16. 458)〕, hyperhomocysteinemia〔OR = 3. 624,95% CI(2. 360,5. 714)〕,hypertension〔OR = 2. 991,95% CI(1. 886,4. 705)〕, diabetes〔OR = 5. 903,95% CI ( 3. 884,9. 025 )〕, elevated LDL 〔 OR = 3. 052,95% CI ( 1. 663,7. 152 )〕 were independent risk factors of the bad prognosis. Conclusion The main clinical symptoms and signs of super - aged patients with posterior circulation ischemic stroke includes dizziness/ vertigo,weakness of extremities,acroparalysis,positive Babinski sign/Chaddock sign,ataxia and central facial paralysis,and lower NIHSS at admission,longer time for seeing a doctor after attack, stroke history,hyperhomocysteinemia,hypertension,diabetes and elevated LDL are influencing factors of the bad prognosis.%目的：探讨超高龄后循环缺血性脑卒中患者的临床特点及其预后影响因素。方法选择2010—2014年张家港市中医医院收治的超高龄后循环缺血性脑卒中患者82例（≥80岁），患者入院后即刻采集性别、年龄、既往史、症状及体征等临床资料，对患者进行美国国立卫生院卒中量表（NIHSS）评分，并详细记录影响患者预后的相关因素，包括高血压、糖尿病、低密度脂蛋白偏高、高同型半胱氨酸血症、冠心病、心房纤颤、心脏瓣膜病、烟酒史及既往卒中史。随访3个月，采用改良 Rankin 量表评价患者预后，并对预后影响因素进行多因素 Logistic 回归分析。结果超高龄后循环缺血性脑卒中患者的主要临床症状为头晕/眩晕（占69.5%）和肢体无力（占68.3%），主要临床体征为肢体瘫痪（占54.9%）、Babinski 征/ Chaddock 征阳性（占46.3%）、共济失调（占43.9%）、中枢性面瘫（占40.2%）。发病后3个月患者预后良好56例（68.3%），预后不良26例（31.7%）。多因素 Logistic 回归分析结果显示，入院时 NIHSS 评分低〔 OR ＝2.648，95% CI（1.552，4.463）〕、发病至就诊时间长〔 OR ＝1.784，95% CI（1.142，2.864）〕、既往有卒中史〔 OR ＝4.402，95% CI（1.165，16.458）〕、高同型半胱氨酸血症〔 OR ＝3.624，95% CI （2.360，5.714）〕、高血压〔 OR ＝2.991，95% CI （1.886，4.705）〕、糖尿病〔 OR ＝5.903，95% CI （3.884，9.025）〕、低密度脂蛋白偏高〔OR ＝3.052，95% CI（1.663，7.152）〕是患者预后不良的独立危险因素。结论超高龄后循环缺血性脑卒中患者最常见的临床症状和体征为头晕/眩晕、肢体无力、肢体瘫痪、Babinski 征/ Chaddock 征阳性、共济失调和中枢性面瘫，且入院时 NIHSS 评分低、发病至就诊时间长、既往有卒中史及合并高同型半胱氨酸血症、高血压、糖尿病、低密度脂蛋白偏高患者多预后不良。
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