血管性认知障碍早期诊断的研究进展

摘要

目的：血管性认知障碍（VCI）涵盖从轻度认知障碍到痴呆全过程，近年来其发病率逐年增高，且痴呆患者由于严重的认知功能障碍而丧失了治疗机会，严重影响患者的生活质量，因此，早期诊断 VCI 具有重要的临床意义。本文介绍了临床评估、神经影像学检查、神经心理评估、生物学标志物等在 VCI 早期诊断中的应用价值，以期为早期诊断 VCI 提供参考。%Vascular cognitive impairment(VCI)rangs from mild cognitive impairment to dementia,and its morbidity increases obviously in recent years. Due to severe cognitive dsyfunction,dementia patients lose the opportunity for treatment, which badly affect the quality of life,so early diagnosis of VCI is of great clinical significance. This paper reviewed the application of clinical assessment,neurological imaging examination,neuropsychological assessment and biomarkers in the early diagnosis of VCI,in order to provide references for clinicians.