Nicotine transdermal patch for smoking cessation using combination of hydrophilic and hydrophobic polymers as matrix film formers

摘要

One of the most popular nicotine replacement therapies (NRTs)available in the market nowadays is the nicotine patches, which provide a source of nicotine to reduce the withdrawal symptoms experienced when smoking is stopped. Nicotine transdermal patch to satisfy addicted smoker’s cravings as oninvasive, self medicated therefore patient compliance and less frequent administration than oral was investigated to contain2 layers;backing layer, adhesive with drug layer.