整合子与细菌耐药相关性研究进展

摘要

Integron is a mobile gene element being found recently. It could recognize drug resistance gene from outside. It can also recombine exogenous gene and express by site-specific recombination. In addition,integron is located at transposon or plasmid,and by being a part of it transmitting drug resistance gene. researches on integron are attracting many interests for its importance in the generation of drug resistance and transmission.%整合子是近年来被发现的一种新的遗传结构元件，能够识别外界的耐药基因，可以通过位点特异性重组的方式捕获耐药基因并使其表达；也可以位于质粒或转座子上，作为质粒或转座子的一个组成部分，在转移的过程中使耐药基因在细菌中发生播散。整合子因为与细菌耐药性的产生和传播关系密切而备受各方的关注。