肠道微生物与人类疾病关系的研究进展

摘要

肠道微生物是寄居于人体肠道的庞大群落,其像是一个器官,具备代谢、免疫和内分泌等多种生理功能,并与人体的其他器官相互作用.在遗传、饮食等外界因素影响下,肠道微生物菌群失调或与人体的平衡被打破,就会导致多种疾病.文章主要从肠道微生物与代谢综合征、心血管疾病、癌症、类风湿性关节炎(RA)以及中枢神经系统疾病的关系进行综述.%Human intestine harbors a large amount of microorganisms(gut microbiome),which works like an organ providing metabolic,immunologic and enter-endocrinal physiological functions and develops commensal relationships with human organism. Under the influence of genetic factors,dietary habits and so on,if the dysbiosis of gut microflora occurs,or the balance with human organism is broken, it would lead to many kinds of diseases. This review mainly shows the relationships between gut microbiome and metabolic syndrome,cardiovascular disease,cancer,rheumatoid arthritis and central nerve system diseases.